"Pyaar Ke Side Effects 1" is a romantic comedy film released in 2006, directed by Saket Chaudhary. The story revolves around the complexities of love and relationships, focusing on the life of a carefree bachelor, Sid, who unexpectedly falls for a strong-willed woman, Trisha. Their journey explores the humorous and challenging side effects of love, highlighting the contrasts between their personalities. The film features notable performances by Rahul Bose as Sid and Mallika Sherawat as Trisha. It combines elements of romance and comedy, making it relatable for audiences navigating the ups and downs of modern relationships. The film's light-hearted approach to serious themes has garnered a positive response from viewers.