Principlism is an ethical framework commonly used in the field of bioethics. It is based on four key principles: autonomy, beneficence, non-maleficence, and justice. These principles guide decision-making in healthcare and research, helping to balance the rights and well-being of individuals with societal needs. The approach was popularized by Tom Beauchamp and James Childress in their book "Principles of Biomedical Ethics." Principlism emphasizes the importance of considering each principle in context, allowing for a flexible yet structured way to address ethical dilemmas in medicine and related fields.