The Prince-Bishops of Brixen were ecclesiastical leaders in the region of Brixen, now part of northern Italy. They held both spiritual and temporal power from the Middle Ages until the 19th century, governing the area as both bishops and princes. Their authority allowed them to influence local politics, economy, and culture, making Brixen an important center in the Tyrol region. These bishops were often involved in conflicts with local nobility and other church leaders, balancing their religious duties with the demands of governance. The role of the Prince-Bishop diminished after the secularization of church lands in the early 19th century, leading to the eventual dissolution of their political power.