"Preacher" is a comic book series created by Garth Ennis and Steve Dillon. It follows the story of Jesse Custer, a small-town preacher who becomes possessed by a supernatural entity called Genesis. This power gives him the ability to command anyone to do his bidding, leading him on a quest to find God and hold Him accountable for abandoning humanity. Throughout his journey, Jesse is joined by his ex-girlfriend Tulip and a hard-drinking vampire named Cassidy. Together, they encounter various characters, including angels and demons, as they explore themes of faith, morality, and redemption in a darkly humorous way.