The Potion of Weakness is a special item in the game Minecraft. It is primarily used to weaken players and mobs, reducing their attack damage. This potion is created by brewing a Fermented Spider Eye with a water bottle, resulting in a potion that can be applied to various entities. When a player or mob drinks the Potion of Weakness, they experience a negative effect that lasts for a limited time. This potion is particularly useful in conjunction with the Golden Apple for curing Zombie Villagers, allowing players to transform them back into their original villager form.