Postural Orthostatic Tachycardia Syndrome (POTS) is a condition that affects the autonomic nervous system, leading to an abnormal increase in heart rate when a person stands up. This can cause symptoms like dizziness, lightheadedness, and fatigue, making it difficult for individuals to maintain their daily activities. POTS is often associated with other conditions, such as Ehlers-Danlos syndrome or Chronic Fatigue Syndrome. Diagnosis typically involves a tilt table test or active stand test to measure heart rate and blood pressure changes. Treatment may include lifestyle changes, increased fluid intake, and medications to help manage symptoms.