Polyfluoroalkyl substances (PFAS) are a group of man-made chemicals used in various industrial and consumer products for their water- and grease-resistant properties. Commonly found in items like non-stick cookware, water-repellent clothing, and food packaging, PFAS have been widely used since the 1950s. These substances are persistent in the environment and can accumulate in the human body over time. Concerns have arisen regarding their potential health effects, including links to certain cancers and other serious health issues. Regulatory agencies are increasingly focusing on PFAS to assess their safety and limit exposure.