Phosphomannose Isomerase is an enzyme that plays a crucial role in carbohydrate metabolism. It catalyzes the conversion of mannose-6-phosphate to fructose-6-phosphate, which is an important step in the process of utilizing sugars for energy. This enzyme is found in various organisms, including humans, and is essential for proper cellular function. Deficiency in Phosphomannose Isomerase can lead to metabolic disorders, such as mannosidosis, which affects the body's ability to break down certain sugars. Understanding this enzyme is important for developing treatments for related conditions and for advancing knowledge in the field of biochemistry.