"Pennsylvania-based" refers to businesses, organizations, or individuals that are located in the state of Pennsylvania. This state, known for its rich history and diverse economy, is home to various industries, including manufacturing, healthcare, and technology. Many well-known companies, such as Hershey and Pittsburgh's UPMC, are Pennsylvania-based. The state's cities, like Philadelphia and Pittsburgh, contribute to its economic landscape, making it a significant player in the northeastern United States.