Paul Modrich is an American biochemist known for his research on DNA repair mechanisms. He was awarded the Nobel Prize in Chemistry in 2015 for his work on how cells correct errors that occur during DNA replication. His discoveries have significantly advanced our understanding of genetic stability and its implications for diseases, including cancer. Modrich earned his Ph.D. from Duke University and has held positions at Duke and the Howard Hughes Medical Institute. His contributions to molecular biology have made him a prominent figure in the scientific community, influencing both research and education in genetics and biochemistry.