PML nuclear bodies are small, spherical structures found within the nucleus of cells. They are named after the promyelocytic leukemia (PML) protein, which is a key component of these bodies. PML nuclear bodies play a crucial role in various cellular processes, including the regulation of gene expression, DNA repair, and the response to stress. These structures are involved in the organization of proteins and RNA within the nucleus, helping to coordinate cellular functions. PML nuclear bodies are also implicated in the response to viral infections and have been studied for their potential role in cancer biology, particularly in leukemia.