PD-L2
PD-L2 is a protein found on the surface of certain cells in the immune system. It plays a crucial role in regulating immune responses by interacting with receptors on T cells, which are essential for fighting infections and diseases. By binding to these receptors, PD-L2 can help prevent the immune system from overreacting, thus maintaining balance and preventing damage to healthy tissues.
PD-L2 is part of the PD-1 pathway, which is important in cancer immunotherapy. Tumors can exploit this pathway to evade immune detection by expressing PD-L2, allowing them to grow unchecked. Understanding PD-L2 is vital for developing treatments that enhance the immune system's ability to target and destroy cancer cells.