P-Glycoprotein
P-Glycoprotein is a membrane protein that plays a crucial role in the transport of various substances across cell membranes. It acts as a pump, moving drugs and other compounds out of cells, which can affect the absorption and distribution of medications in the body. This function is particularly important in organs like the liver and intestines, where it helps regulate the entry of drugs into the bloodstream.
The activity of P-Glycoprotein can influence the effectiveness of certain medications, as some drugs may be expelled from cells before they can exert their therapeutic effects. Variations in P-Glycoprotein expression among individuals can lead to differences in drug responses, making it a significant factor in personalized medicine and pharmacology.