Ozone layer depletion refers to the thinning of the ozone layer, a protective region in the Earth's atmosphere that absorbs most of the sun's harmful ultraviolet (UV) radiation. This depletion is primarily caused by human-made chemicals, particularly chlorofluorocarbons (CFCs), which are found in products like aerosol sprays and refrigerants. When these substances reach the stratosphere, they break down ozone molecules, leading to a decrease in the layer's thickness. The consequences of ozone layer depletion include increased UV radiation reaching the Earth's surface, which can lead to higher rates of skin cancer, cataracts, and other health issues. Additionally, it can harm ecosystems, particularly marine life and plant growth. Efforts to reduce the use of CFCs and other ozone-depleting substances have been implemented through international agreements like the Montreal Protocol, which aims to protect the ozone layer and promote environmental health.