The Owens sisters, Gilliam Owens and Samantha Owens, are fictional characters from the novel "Practical Magic" by Alice Hoffman. They are part of a family of witches who face various challenges due to their magical abilities and the societal stigma surrounding them. The story explores themes of love, loss, and the bond between sisters. In the narrative, the Owens sisters navigate their lives while dealing with the legacy of their family's history. Their journey highlights the importance of embracing one's identity and the power of sisterhood. The novel has also been adapted into a film, further popularizing the characters and their story.