The Osage River is a major river located in central Missouri, USA. It flows approximately 276 miles and is a tributary of the Missouri River. The river is known for its scenic beauty and recreational opportunities, including fishing, boating, and camping along its banks. The Osage River is formed by the confluence of the Osage Fork and Grand River. It passes through several towns, including Osage Beach and Lake Ozark, and is an important waterway for local ecosystems and communities. The river also plays a role in regional history and culture, particularly for the Osage Nation.