Organic cation transporters (OCTs) are proteins found in cell membranes that facilitate the movement of organic cations, which are positively charged molecules, into and out of cells. These transporters play a crucial role in the absorption, distribution, and excretion of various drugs and metabolites, influencing pharmacokinetics and drug interactions. OCTs are primarily located in organs such as the kidneys, liver, and intestines. They help regulate the levels of neurotransmitters and other important compounds in the body. Dysfunction or genetic variations in OCTs can lead to altered drug responses and contribute to various health conditions.