Ohio State Route 16 is a major east-west highway in the state of Ohio. It stretches approximately 90 miles, connecting the city of Zanesville in the east to Newark in the west. The route serves as an important corridor for local traffic and commerce, facilitating travel across several counties. The highway runs through various landscapes, including rural areas and small towns. It intersects with several other major routes, enhancing connectivity within the region. Ohio State Route 16 is also known for its scenic views, making it a pleasant drive for both residents and visitors.