OCT1, or Organic Cation Transporter 1, is a protein that plays a crucial role in the transport of organic cations across cell membranes. It is primarily found in the liver and kidneys, where it helps in the uptake and elimination of various substances, including drugs and metabolites. This transporter is essential for maintaining the balance of organic compounds in the body. The function of OCT1 is significant in pharmacology, as it influences how the body processes certain medications. Variations in the OCT1 gene can affect individual responses to drugs, leading to differences in efficacy and side effects. Understanding OCT1 is important for personalized medicine and optimizing drug therapy.