A Nucleoside Reverse Transcriptase Inhibitor (NRTI) is a class of antiretroviral drugs used primarily to treat HIV infections. These medications work by mimicking the building blocks of DNA, which prevents the virus from replicating its genetic material. By inhibiting the enzyme reverse transcriptase, NRTIs help reduce the viral load in the body. Common examples of NRTIs include Zidovudine, Lamivudine, and Tenofovir. These drugs are often used in combination with other antiretroviral therapies to enhance their effectiveness and minimize the development of drug resistance. Regular monitoring and adherence to treatment are essential for optimal outcomes.