Nuclear architecture refers to the organization and structure of the nucleus within a cell. It involves the arrangement of chromatin, which is the material made of DNA and proteins, and how it is spatially organized to regulate gene expression and cellular functions. This architecture plays a crucial role in maintaining the integrity of genetic information. The nuclear envelope surrounds the nucleus, separating it from the cytoplasm. It consists of two membranes and contains nuclear pores that control the movement of molecules in and out of the nucleus. Understanding nuclear architecture is essential for studying cellular processes and diseases, including cancer.