In the manga and anime series Monthly Girls' Nozaki-kun, Nozaki's assistants refer to the characters who help Umetarou Nozaki, a high school student and manga artist, with his work. The main assistants include Chiyo Sakura, a classmate who has a crush on Nozaki, and Mikoto Mikoshiba, a popular boy who often provides comedic relief. Each assistant contributes uniquely to the creative process, often leading to humorous situations. The interactions between Nozaki and his assistants highlight the challenges of creating manga while balancing personal relationships. Their teamwork showcases the dynamics of friendship and collaboration, as they navigate the ups and downs of the manga industry together.