The Northern Rebellion of 1569 was a significant uprising in England, primarily involving the northern counties. It was led by noble families, including the Percys and Nevilles, who opposed the rule of Queen Elizabeth I and sought to place Mary, Queen of Scots on the English throne. The rebellion aimed to restore Catholicism and challenge the Protestant establishment. The revolt began in November 1569 but was quickly suppressed by government forces. Many rebels were executed or imprisoned, and the failure of the rebellion solidified Elizabeth I's power. The event highlighted the tensions between Catholics and Protestants during this period in English history.