"Night at the Museum" is a family-friendly film that follows a night guard named Larry Daley, played by Ben Stiller. He discovers that the exhibits in the American Museum of Natural History come to life after dark due to a magical tablet. As he navigates this unusual situation, he encounters various historical figures and creatures, including Teddy Roosevelt and a Tyrannosaurus rex skeleton. Throughout the night, Larry must manage the chaos created by the animated exhibits while trying to keep his job. The film combines humor and adventure, showcasing the importance of history and imagination in a fun and engaging way.