Negishi Coupling is a chemical reaction that allows for the formation of carbon-carbon bonds. It involves the coupling of an organozinc compound with an organic halide, typically in the presence of a palladium catalyst. This method is valuable in organic synthesis for creating complex molecules. The reaction is named after Akira Negishi, who was awarded the Nobel Prize in Chemistry in 2010 for his contributions to the development of this coupling technique. Negishi Coupling is particularly useful in the pharmaceutical and materials science industries, enabling the construction of diverse and functionalized organic compounds.