Naive T Cells are a type of immune cell that have not yet encountered their specific antigen. They originate from the bone marrow and mature in the thymus, where they develop the ability to recognize specific pathogens. These cells circulate through the bloodstream and lymphatic system, ready to respond to infections. When Naive T Cells encounter their specific antigen presented by Antigen-Presenting Cells, they become activated. This activation leads to their differentiation into effector T cells, which help eliminate pathogens, or memory T cells, which provide long-term immunity. This process is crucial for the adaptive immune response.