NSD2 is a gene that encodes a protein involved in the regulation of gene expression and RNA processing. It plays a crucial role in the development and function of various tissues, particularly in the nervous system. Mutations in the NSD2 gene can lead to developmental disorders and other health issues. The NSD2 protein is part of a larger family of proteins known as SET domain proteins, which are important for modifying histones and influencing chromatin structure. This modification can affect how genes are turned on or off, impacting cellular processes and overall organismal development.