NFL Fantasy is a game where participants create their own virtual teams using real players from the National Football League. Each week, players earn points based on their actual performance in games, such as touchdowns, yards gained, and receptions. Participants typically join leagues with friends or online communities, drafting players and managing their rosters throughout the NFL season. The goal is to score more points than other teams in the league, leading to weekly matchups and an overall championship at the end of the season.