The "Mother Road" is a nickname for U.S. Route 66, a historic highway in the United States that originally ran from Chicago, Illinois to Santa Monica, California. Established in 1926, it became a symbol of freedom and adventure, connecting rural communities and bustling cities across eight states. Route 66 played a significant role in American culture, especially during the Great Depression and the post-World War II era, as it facilitated migration and travel. Today, it is celebrated for its nostalgic charm, featuring vintage diners, motels, and roadside attractions that reflect the spirit of mid-20th century America.