Mixed strategies are a concept in game theory where players randomize their choices to keep opponents uncertain about their next move. Instead of sticking to a single strategy, players select from multiple options with specific probabilities. This approach can help achieve better outcomes in competitive situations, as it prevents predictability. In games like rock-paper-scissors, using a mixed strategy can enhance a player's chances of winning. By varying their choices, players make it difficult for opponents to anticipate their actions, leading to a more balanced and strategic gameplay experience.