The Middle Loup River is a tributary of the Loup River located in central Nebraska, USA. It flows approximately 100 miles through the Sandhills region, characterized by rolling sand dunes and grasslands. The river is an important water source for local agriculture and wildlife. The river's watershed supports various ecosystems and is home to species such as fish and birds. The Middle Loup River also plays a role in recreational activities, including fishing and kayaking, attracting outdoor enthusiasts to the area. Its scenic beauty and natural resources contribute to the region's ecological health.