The Middle Cerebral Artery (MCA) is one of the major arteries supplying blood to the brain. It branches off from the internal carotid artery and primarily provides oxygen and nutrients to the lateral aspects of the cerebral hemispheres, including areas responsible for movement, sensation, and language. The MCA is clinically significant because it is commonly involved in ischemic strokes, which occur when blood flow is blocked. Symptoms of an MCA stroke can include weakness on one side of the body, difficulty speaking, and changes in sensory perception, highlighting its crucial role in brain function.