Lymphocyte Trafficking
Lymphocyte trafficking refers to the movement of lymphocytes, a type of white blood cell, throughout the body. These cells play a crucial role in the immune system by identifying and responding to pathogens. Lymphocytes circulate through the bloodstream and migrate to various tissues, including lymph nodes and the spleen, where they can encounter antigens and become activated.
The process of lymphocyte trafficking involves several steps, including rolling, adhesion, and transmigration through blood vessel walls. This movement is guided by specific signals, such as chemokines and adhesion molecules, which help direct lymphocytes to sites of infection or inflammation, ensuring an effective immune response.