"Lives of the Mayfair Witches" is a supernatural drama series based on the novels by Anne Rice. It follows the lives of a family of witches known as the Mayfair clan, who possess unique powers and face various challenges related to their magical heritage. The story explores themes of witchcraft, family dynamics, and the struggle for identity. The main character, Rowan Mayfair, is a talented neurosurgeon who discovers her witch lineage and the dark secrets that come with it. As she navigates her newfound abilities, she encounters both allies and adversaries, leading to a deeper understanding of her family's legacy and the responsibilities that accompany their powers.