Ligases are a type of enzyme that play a crucial role in the process of DNA replication and repair. They facilitate the joining of two large molecules by forming a bond between them, typically linking the ends of DNA strands. This action is essential for maintaining the integrity of the genetic material within cells. In addition to their role in DNA, ligases are also involved in various biochemical pathways, including the synthesis of RNA and the metabolism of lipids. By catalyzing the formation of covalent bonds, ligases help ensure that cellular processes function smoothly and efficiently.