Laser capture microdissection (LCM) is a technique used to isolate specific cells or tissue regions from a larger sample using a focused laser beam. This method allows researchers to precisely cut and collect targeted cells while preserving their molecular integrity for further analysis. The process typically involves placing a thin slice of tissue on a special slide, then using a laser to cut around the desired cells. Once isolated, these cells can be analyzed for DNA, RNA, or protein content, making LCM a valuable tool in fields like cancer research and genomics.