Lake Santa Fe is a large freshwater lake located in Alachua County, Florida. It covers approximately 6,000 acres and is known for its scenic beauty and recreational opportunities. The lake is surrounded by lush vegetation and offers habitats for various wildlife species. The lake is popular for activities such as fishing, boating, and swimming. It is home to several fish species, including largemouth bass and bluegill. Additionally, Lake Santa Fe is a part of the Santa Fe River watershed, contributing to the area's natural ecosystem and water resources.