The Knoxville Metropolitan Statistical Area (MSA) is located in eastern Tennessee and includes Knox County as its core. It encompasses several surrounding counties, including Anderson, Blount, Loudon, and Sevier. The area is known for its diverse economy, which includes sectors like education, healthcare, and manufacturing. The MSA is home to the city of Knoxville, which is the largest city in the region. It also features attractions such as the Great Smoky Mountains National Park and the University of Tennessee. The population of the Knoxville MSA is approximately 500,000 residents, making it a significant urban center in the state.