Kirksville Regional Airport is located in Kirksville, Missouri, and serves as a key transportation hub for the region. The airport features a single asphalt runway and offers commercial flights, primarily connecting to larger airports. It also accommodates general aviation and private aircraft. The airport is managed by the City of Kirksville and plays an important role in supporting local businesses and tourism. It is situated near several attractions, including Truman State University and Thompson River, making it a convenient entry point for visitors to the area.