The "Kanker Sisters" are fictional characters from the animated television series Ed, Edd n Eddy. They are known for their distinctive appearance, which includes large heads, sharp teeth, and a mischievous demeanor. The sisters often serve as antagonists in the show, frequently bullying the main characters, Ed, Edd, and Eddy. The Kanker Sisters consist of three characters: May, Lee, and Marie. Each sister has her own unique personality traits, with May being the most playful, Lee being tough and assertive, and Marie being the most cunning. Their interactions with the boys often lead to humorous and chaotic situations throughout the series.