KCNJ12 is a gene that provides instructions for making a protein known as an inwardly rectifying potassium channel. This protein plays a crucial role in regulating the flow of potassium ions in and out of cells, which is essential for maintaining the electrical balance and proper functioning of cells, particularly in the heart and brain. Mutations in the KCNJ12 gene can lead to various health issues, including certain types of cardiac arrhythmias. These conditions can disrupt the normal rhythm of the heart, potentially leading to serious complications. Understanding KCNJ12 is important for research in genetics and medicine, particularly in the field of cardiology.