Irene and Isaac Bernheim were prominent figures in the Bernheim family, known for their contributions to the Kentucky bourbon industry. They played a significant role in the development of the Bernheim Distillery, which is recognized for producing high-quality bourbon and whiskey. The Bernheims were also involved in various philanthropic efforts, supporting local communities and cultural institutions. Their legacy continues through the Bernheim Arboretum and Research Forest, a natural area dedicated to conservation and education, reflecting their commitment to both the environment and the community.