Interleukin-1α (IL-1α) is a type of protein known as a cytokine, which plays a crucial role in the immune system. It is produced by various cells, including macrophages and keratinocytes, and helps regulate inflammation and immune responses. IL-1α is involved in the activation of immune cells and the promotion of inflammatory processes, making it important for fighting infections and healing injuries. In addition to its role in immune responses, IL-1α is implicated in various diseases, including autoimmune disorders and chronic inflammatory conditions. Elevated levels of IL-1α can contribute to tissue damage and inflammation, highlighting its significance in both health and disease management.