IL-1 inhibitors are a class of medications designed to block the activity of interleukin-1 (IL-1), a protein that plays a key role in inflammation and immune responses. By inhibiting IL-1, these drugs help reduce inflammation and alleviate symptoms in various autoimmune and inflammatory conditions, such as rheumatoid arthritis and gout. These inhibitors can be administered through injections or infusions and are often used when other treatments are ineffective. Common examples include anakinra and canakinumab. Overall, IL-1 inhibitors represent an important therapeutic option for managing chronic inflammatory diseases.