Hydrochloride refers to a chemical compound formed when hydrochloric acid reacts with a base, typically an amine. This process results in a salt that is often more stable and soluble in water than the original amine. Hydrochlorides are commonly used in pharmaceuticals to enhance the absorption and effectiveness of medications. In the medical field, many drugs are available in hydrochloride form, such as sertraline hydrochloride and diphenhydramine hydrochloride. These compounds help ensure that the active ingredient is delivered effectively in the body, making them essential in the formulation of various treatments.