The House of Medici was a powerful and influential family in Florence, Italy, during the Renaissance. They rose to prominence in the 15th century through banking and commerce, becoming one of the wealthiest families in Europe. Their financial success allowed them to become patrons of the arts and supporters of notable artists like Leonardo da Vinci and Michelangelo. The Medici family produced four popes, including Pope Leo X, and played a significant role in the political landscape of Italy. Their influence extended beyond Florence, impacting the broader cultural and political developments of the Renaissance period.