The House of Farnese was an influential Italian noble family that rose to prominence during the Renaissance. Originating in the 15th century, they became known for their political power, wealth, and patronage of the arts. The family produced several notable figures, including Pope Paul III, who was instrumental in the Counter-Reformation. The Farnese were also significant landowners, with vast estates in Italy. Their legacy includes impressive architectural achievements, such as the Palazzo Farnese in Rome and the Farnese Palace in Caprarola. The family's contributions to culture and politics left a lasting impact on Italian history.