Holt County is located in north-central Nebraska and is part of the Sandhills region. Established in 1857, it covers an area of approximately 2,400 square miles, making it one of the largest counties in the state. The county seat is O'Neill, which is known for its Irish heritage and hosts the annual O'Neill St. Patrick's Day Celebration. The county's economy is primarily based on agriculture, with cattle ranching and crop production being significant contributors. Holt County is home to several parks and recreational areas, offering opportunities for outdoor activities such as fishing and hiking. The Niobrara River runs through the county, adding to its natural beauty.