Hemoglobin derivatives are modified forms of hemoglobin, the protein in red blood cells responsible for transporting oxygen. These derivatives can form when hemoglobin interacts with various substances, such as carbon monoxide or glucose. Common examples include carboxyhemoglobin, which occurs when hemoglobin binds with carbon monoxide, and glycosylated hemoglobin, which is formed when glucose attaches to hemoglobin, often used to monitor diabetes. The presence of hemoglobin derivatives can affect the oxygen-carrying capacity of blood. For instance, carboxyhemoglobin reduces the ability of hemoglobin to release oxygen to tissues, leading to potential health issues. Monitoring these derivatives is crucial in clinical settings to assess and manage various health conditions.