Hedgehog Signaling
Hedgehog Signaling is a crucial communication pathway in cells that helps regulate growth and development in many organisms, including humans. It plays a significant role in processes like embryonic development, tissue regeneration, and cell differentiation. The pathway is named after the Hedgehog gene, which was first discovered in fruit flies and is essential for proper body patterning.
In this signaling pathway, a protein called Sonic Hedgehog (Shh) binds to a receptor on the cell surface, triggering a series of events that influence gene expression. Dysregulation of Hedgehog signaling can lead to various diseases, including certain types of cancer, making it an important area of study in developmental biology and medicine.